Brazilin from Caesalpinia sappan heartwood and its pharmacological activities: A review
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چکیده
منابع مشابه
Pharmacognostical Evaluation of Caesalpinia sappan Heartwood
Caesalpinia span heartwood is used in folklore in India. The present work attempts to summarize the pharmacognostical characters of the heartwood of this plant. Ash and extractive values, phytochemical tests, HPTLC and fluorescence analysis were carried out. The present work contributes for the standardization of this medicinal heat wood.
متن کاملContact dermatitis caused by brazilin in Caesalpinia sappan.
A 49-year-old woman presented with an eczematous reaction on her hands that which had appeared 5 days previously. To treat her wrist sprain, she had applied hot compresses with a herbal water decoction of multi-ingredient formulations on her hands for half an hour, and bathed her hands in this decoction for another 20min. After 1 day, her hands became erythematous, with burning and itching (Fig...
متن کاملEVALUATION OF ANTI-CANCER PROPERTIES OF HEARTWOOD OF Caesalpinia sappan
Objectives: To evaluate the anti-cancer potential of the heartwood of Caesalpinia sappan. Methods: The extraction of the plant material was done using ethyl acetate, methanol and water. Cytotoxicity evaluated using MTT assay. Apoptosis potential was evaluated by cell cycle analysis and Hoechst staining techniques. In vivo anticancer evaluation performed by the Ehrlich’s ascites carcinoma model ...
متن کاملBrazilin Isolated from Caesalpinia sappan suppresses nuclear envelope reassembly by inhibiting barrier-to-autointegration factor phosphorylation.
To date, many anticancer drugs have been developed by directly or indirectly targeting microtubules, which are involved in cell division. Although this approach has yielded many anticancer drugs, these drugs produce undesirable side effects. An alternative strategy is needed, and targeting mitotic exit may be one alternative approach. Localization of phosphorylated barrier-to-autointegration fa...
متن کاملA new 3-benzylchroman derivative from Sappan Lignum (Caesalpinia sappan).
3'-Deoxy-4-O-methylepisappanol, a new 3-benzylchroman derivative, was isolated from Sappan Lignum, together with thirteen known chemical compounds identified as protosappanin A, sappanchalcone, sappanone B, palmitic acid, (+)-(8S,8'S)-bisdihydrosiringenin, brazilein, 3-deoxysappanchalcone, (+)-lyoniresinol, 3-deoxysappanone B, protosappanin B, isoprotosappanin B, 3'-O-methylbrazilin and brazili...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Medicine
سال: 2015
ISSN: 1995-7645
DOI: 10.1016/j.apjtm.2015.05.014